LEZOXIB 200MG CAPSULE ONLINE AT BEST PRICE IN PAKISTAN

GENERIC: Celecoxib 200mg

MANUFACTURER: Horizon Pharma

QUANTITY:

Pack of 30 tablets

INDICATION

Lezoxib 200mg Cap is a selective COX-2 inhibitor used in the management of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and primary dysmenorrhea. The 200mg strength is the standard adult dose for arthritis management and offers convenient once or twice-daily dosing with a gastrointestinal safety advantage over non-selective NSAIDs.

MECHANISM OF ACTION

Celecoxib selectively blocks COX-2 without significantly inhibiting COX-1, reducing the synthesis of prostaglandins responsible for pain, inflammation, and fever while preserving the gastroprotective prostaglandins produced by COX-1 in the gastric mucosa. The 200mg dose achieves therapeutic plasma concentrations adequate for both acute and chronic inflammatory conditions, with sustained anti-inflammatory and analgesic effect throughout the dosing interval.

DOSAGE AND ADMINISTRATION

• Osteoarthritis: 200mg once daily

• Rheumatoid arthritis: 100 to 200mg twice daily

• Acute pain/dysmenorrhea: 400mg as initial dose, then 200mg twice daily

• Always use the minimum effective dose; follow your doctor's dosing instructions closely

SIDE EFFECTS

Common:

• Headache and dizziness

• Abdominal pain, dyspepsia, nausea

• Diarrhoea

• Peripheral oedema

Less common:

• Cardiovascular events (myocardial infarction, stroke) with prolonged use

• Hypertension

• Hepatotoxicity and elevated liver enzymes

• Severe skin reactions (rare): Stevens-Johnson syndrome, toxic epidermal necrolysis

NOT RECOMMENDED IN

• Known allergy to celecoxib, sulfonamides, or aspirin/NSAIDs

• Active gastric or duodenal ulcer

• Severe hepatic or renal impairment

• Patients with cardiovascular disease or high cardiovascular risk

DRUG INTERACTIONS

Fluconazole significantly increases celecoxib plasma levels through CYP2C9 inhibition; halve the celecoxib dose. Warfarin: monitor INR closely as celecoxib may increase anticoagulant effect. ACE inhibitors and diuretics may lose efficacy. Aspirin at analgesic doses combined with celecoxib negates the GI safety advantage and increases ulcer risk.

STORAGE INSTRUCTIONS

Store below 30°C in a dry, light-protected place. Keep in original packaging. Keep out of reach of children.

WHERE TO BUY

You can buy Lezoxib 200mg cap online from Dawa Healthcare Pharmacy at dawahealthcare.biz, Pakistan's trusted source for authentic medicines with pharmacist-verified products. Check the Lezoxib 200mg cap price in Pakistan and learn about Lezoxib 200mg capsule uses directly on our product page. Our knowledgeable pharmacy team is available to answer all your questions about dosage, uses, and suitability. Same-day delivery is available for customers in Karachi, ensuring you receive your order without delay. For customers across Pakistan, Dawa Healthcare offers reliable nationwide courier service so your medicine reaches you safely and on time. You can also visit any of our Karachi branches in person or contact our responsive WhatsApp support team for quick help with Lezoxib 200mg capsule uses, pricing, and order placement.

Celecoxib200mg